Giant Papillary Conjunctivitis (GPC)?

Giant papillary conjunctivitis (GPC) is a chronic, allergic eye condition that causes inflammation and the growth of large, fleshy bumps (papillae) on the inside of the upper eyelid. These papillae can rub against the cornea, the clear front cover of the eye, and cause symptoms such as itching, burning, redness, and a feeling of something in the eye.

GPC is commonly caused by an allergic reaction to proteins found in certain substances, such as:

Contact lens wear: GPC is particularly associated with extended wear of soft contact lenses. The proteins and deposits that accumulate on the lenses can trigger an allergic reaction in the conjunctiva.

Eye drops or medications: Some eye drops or medications, such as glaucoma medications, can cause GPC as a side effect.

Surgical sutures: GPC can sometimes develop after eye surgery, particularly if sutures are used.

Other allergens: Exposure to other allergens, such as pollen, dust, or pet dander, can also contribute to GPC.

Symptoms of GPC may include:

Itching

Burning

Redness

Swollen eyelids

A feeling of something in the eye

Excessive tearing

Blurred vision

Sensitivity to light

GPC is usually diagnosed based on the patient's symptoms and an examination of the eye by an eye doctor. The eye doctor may use a special dye to highlight the papillae and confirm the diagnosis.

Treatment for GPC typically involves avoiding the allergen causing the reaction and managing the symptoms. Treatment options may include:

Discontinuing contact lens wear or switching to a different type of lens

Avoiding allergens, such as pollen or dust

Using artificial tears to relieve dryness and irritation

Applying cold compresses to reduce swelling

Using antihistamine eye drops or oral antihistamines to reduce itching and inflammation

In severe cases, surgery may be necessary to remove the papillae.

GPC can usually be managed effectively with proper treatment and avoidance of the allergen. Contact lens wearers should follow proper lens care instructions and see their eye doctor regularly to monitor for any signs of GPC.